Protoporphyrin IX

Referentie 241378-250mg

Formaat : 250mg

Merk : US Biological

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241378 Protoporphyrin IX

Clone Type
Polyclonal
Grade
Highly Purified
Shipping Temp
RT
Storage Temp
4°C

Protoporphyrin IX is an important precursor to biologically essential prosthetic groups such as heme, cytochrome c, and chlorophylls. As a result, a number of organisms are able to synthesize this tetrapyrrole from basic precursors such as glycine and succinyl CoA, or glutamate. Despite the wide range of organisms that synthesize protoporphyrin IX the process is largely conserved from bacteria to mammals with a few distinct exceptions in higher plants.||Synonyms:|Protoporphyrin IX; 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic Acid; Kammerer's Porphyrin; Levulan; NSC 177389; NSC 2632; Ooporphyrin; Protoporphyrin||CAS No:|553-12-8||Molecular Formula:|C34H34N4O4||Molecular Weight:|562.67||Purity (HPLC):|≥97%||Appearance:|Dark reddish brown powder||Solubility:|DMSO (≤2mg/mL), Water (≤1mg/ml)||Storage and Stability:|Store at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Applications
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. ||Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. A. R. Battersby; C. J. R. Fookes; G. W. J. Matcham; E. McDonald (1980). "Biosynthesis of the pigments of life: formation of the macrocycle". Nature. 285: 17–21. doi:10.1038/285017a0. 2. F. J. Leeper (1983). "The biosynthesis of porphyrins, chlorophylls, and vitamin B12". Natural Product Reports. 2: 19–47. doi:10.1039/NP9850200019. 3. G. Layer; J. Reichelt; D. Jahn (2010). "Structure and function of enzymes in heme biosynthesis". Protein Science. 19: 1137–1161. doi:10.1002/pro.405.

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241378-1g
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