Recombinant Mouse TNF-α Protein (HEK293)
Referentie M10115-10ug
Formaat : 10ug
Merk : AbMole Bioscience
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TNFSF2
Quality Control & Documentation
Biological Activity
TNF-α (HEK293) is a pleiotropic pro-inflammatory cytokine secreted by a variety of cells such as adipocytes, activated monocytes, macrophages, B cells, T cells, and fibroblasts. TNF-α is cytotoxic to a variety of tumor cells and is an important factor that mediates the immune response to bacterial infections. TNF-α also plays a role in the induction of septic shock, autoimmune diseases, rheumatoid arthritis, inflammation and diabetes.
Measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells, the ED50 is < 0.05 ng/ml, corresponding to a specific activity of > 2.0 × 107 units/mg.
Accession: P06804
Apparent Molecular Weight: ~17.3 kDa, under reducing conditions
Endotoxin < 0.2 EU/μg
Lyophilized after extensive dialysis against PBS.
Chemical Information
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml. |
| Storage | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |