fr en es de it pt nl

Reagentia en instrumenten voor immunologie, celbiologie en moleculaire biologie.

Ruxolitinib phosphate [1092939-17-7]

Afdrukken

Referentie A3781-1ml

Formaat : 10mM(in1mLDMSO)

Neem contact op met een lokale distributeur :

Telefoonnummer : +1 850 650 7790

Merk : APExBIO Technology

Meer informatie aanvragen

Neem contact op met een lokale distributeur :

Telefoonnummer : +1 850 650 7790

<div class="message global noscript"><div class="content"><p><strong>JavaScript seems to be disabled in your browser.</strong> <span>For the best experience on our site, be sure to turn on Javascript in your browser.</span></p></div></div>

Background

INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor .(IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively).INCB018424 is useful for rheumatoid arthritis.

Chemical Properties

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	404.36
Cas No.	1092939-17-7
Formula	C₁₇H₂₁N₆O₄P
Synonyms	INCB018424 phosphate;INCB 018424 phosphate;INCB-018424 phosphate;Ruxolitinib
Solubility	≥20.2 mg/mL in DMSO; ≥6.92 mg/mL in EtOH with gentle warming and ultrasonic; ≥8.03 mg/mL in H2O with gentle warming and ultrasonic
Chemical Name	(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
SDF	Download SDF
Canonical SMILES	[HH].C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OOP(=O)=O
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Purity = 99.87%