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- Specifications
Product Description
Human TNFAIP3 full-length ORF ( AAH98379.1, 1 a.a. - 248 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISGEMPADHGSVLKCFQPYALAPGENHTAKVQVTEFNGI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
55.3
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
- Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
- Gene Info — TNFAIP3
Entrez GeneID
7128GeneBank Accession#
BC098379.1Protein Accession#
AAH98379.1Gene Name
TNFAIP3
Gene Alias
A20, MGC104522, MGC138687, MGC138688, OTUD7C, TNFA1P2
Gene Description
tumor necrosis factor, alpha-induced protein 3
Omim ID
191163Gene Ontology
HyperlinkGene Summary
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. Knockout studies of a similar gene in mice suggested that this gene is critical for limiting inflammation by terminating TNF-induced NF-kappa B responses. [provided by RefSeq
Other Designations
OTTHUMP00000017289|tumor necrosis factor inducible protein A20
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