HLA-DR is a heterodimer composed of 36 kDa α chain and 27 kDa β chain, encoded by the MHC gene complex on the short arm of chromosome 6. The two chains can appear in many different allelic morphologies and are highly polymorphic. HLA-DR is structurally expressed in antigen-presenting cells, mainly in immune system cells^[1]. HLA-DR was strongly expressed in monocytes, especially in CD14+ CD16+ subgroups^[2]. It can also be expressed in macrophages, granulocytes, plasmoid dendritic cells, microglia and Langerhans' cells^[1,3,4]. HLA-DR can also be expressed in the immature hematopoietic cells, such as BFU-E, but not in CFU-E or proerythroblast[5]. This product is the mouse anti-human HLA-DR monoclonal antibody, which is used for the specific detection of human HLA-DR by IF and FC.

Storage

PBS (pH7.4), 150 mM NaCl, 0.05% ProClin 300, 50% Glycerol; at -20oC for two years, avoid repeated freeze-thawing.

Shipping

Dry ice (-70℃)