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> Type IV Collagen Antibody : Biotin

Type IV Collagen Antibody : Biotin

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Referentie OASB02744

Formaat : 0.2mg

Merk : Aviva Systems Biology

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Datasheets/ManualsPrintable datasheet for Type IV Collagen Antibody : Biotin (OASB02744)
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityMouse, Rat, Canine, Chicken, Chinchilla, Equine, Guinea Pig, Japanese Macaque, Porcine, Rabbit, Sheep, Tree Shrew
Product FormatLiquid. Phosphate buffered saline containing 0.1% sodium azide
ClonalityPolyclonal
HostGoat
ConjugationBiotin
ApplicationEM, FC, ICC, IHC-F, IHC-P, IP, WB
Additional InformationDescription: Pooled antisera from goats hyperimmunized with type IV collagen; purified by affinity chromatography on type IV collagen covalently linked to agarose; reacts with conformational determinants on type IV collagen; cross-adsorbed against Collagen types I, II, III, V, and VI for minimal reactivity
Reconstitution and StorageStore at 2-8C
ImmunogenType IV collagen
Concentration0.4 mg/mL
SpecificityType IV Collagen
Gene SymbolCOL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6
Gene Full Namecollagen type IV alpha 1 chain
Alias SymbolsBSVD, BSVD1, RATOR, PADMAL, COL4A1s
NCBI Gene Id1282; 1284; 1285; 1286; 1287; 1288
Protein Namecollagen alpha-1(IV) chain
Description of TargetThis gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.
Uniprot IDP02462, P08572, Q01955, P53420, P29400, Q14031
Protein Accession #NP_001290039.1
Nucleotide Accession #NM_001303110.1

  1. What is the species homology for "Type IV Collagen Antibody : Biotin (OASB02744)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Mouse, Rat, Canine, Chicken, Chinchilla, Equine, Guinea Pig, Japanese Macaque, Porcine, Rabbit, Sheep, Tree Shrew".

  2. How long will it take to receive "Type IV Collagen Antibody : Biotin (OASB02744)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "Type IV Collagen Antibody : Biotin (OASB02744)" provided in?

    This item is provided in "Liquid. Phosphate buffered saline containing 0.1% sodium azide".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Type IV Collagen Antibody : Biotin (OASB02744)"?

    This target may also be called "BSVD, BSVD1, RATOR, PADMAL, COL4A1s" in publications.

  5. What is the shipping cost for "Type IV Collagen Antibody : Biotin (OASB02744)"?

    The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.

  6. What is the guarantee for "Type IV Collagen Antibody : Biotin (OASB02744)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Type IV Collagen Antibody : Biotin (OASB02744)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Type IV Collagen Antibody : Biotin (OASB02744)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.