UVRAG (389-699) Mouse Monoclonal Antibody [Clone ID: 1H4]

Specifications

Product Data
Clone Name	1H4
Applications	IP, WB
Recommended Dilution	Western blot: 1 μg/ml for chemiluminescence detection system.  Positive Control: HeLa, Jurkat (Human), NIH/3T3, WR19L (Mouse), Rat1 (Rat), and CHO (Hamster). Immunoprecipitation: 5 μg/300 μl of cell extract from 1 x 107 cells.
Reactivities	Hamster, Human, Mouse, Rat
Host	Mouse
Isotype	IgG2a
Clonality	Monoclonal
Immunogen	Recombinant protein corresponding to amino acid residues 389 to 699 of Human UVRAG
Specificity	This antibody reacts with UVRAG.
Formulation	PBS containing 50% glycerol, pH 7.2. No preservative is contained. State: Azide Free State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A Agarose
Conjugation	Unconjugated
Storage	Upon receipt, store (in aliqouts) at -20°C. Avoid repeated freezing and thawing.
Stability	Shelf life: One year from despatch.
Gene Name	UV radiation resistance associated
Database Link	Entrez Gene 7405 Human UniProt ID Q9P2Y5
Background	Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. UVRAG (UV irradiation resistance-associated gene) has been identified as an essential component of the Beclin 1-PI3KC3 complex that suppresses tumorigenicity of human colon and promotes Beclin 1 dependent autophagy.
Synonyms	p63
Note	This product was originally produced by MBL International.
Reference Data