Thyroid adenoma with accumulation of throglobulin positive masses.Thyroglobulin negative anaplastic thyroid carcinoma.Follicular thyroid carcinoma with luminal throglobulin staining.Papillary thyroid carcinoma with mosaic-like cytoplasmic staining.
  • SKU DIA-TGN-OD
    Specificity

    Thyroglobulin
    Species Reactivity

    Human
    Host Species

    Mouse
    Isotype

    IgG1
    Clone

    JGN3
    Clonality (Mono-/Polyclonal)

    monoclonal
    Application

    Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections)
    Conjugation

    unconjugated
    Dilution

    Immunohistochemistry (IHC): 1:100 – 1:400
    Format

    < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
    Product line / Topic

    Tumor Marker / Biology
    Intended Use

    for Research Use Only
    Temperature - Storage

    2-8°C
    Temperature - Transport

    cooled
    Search Code

    DIATGN, IHC, FFPE, Paraffin, Thyroglobulin
    Manufacturer / Brand

    dianova
    Uniprot_ID

    P01266
    Gene_ID

    7038
    Alias

    AITD3, hTG, TDH3, TG, TGN, Thyroglobulin
  • Mouse monoclonal anti-Thyroglobulin antibody clone JGN3 is suitable for the immunohistological detection of Thyroglobulin in routine-fixed paraffin embedded tissue sections Thyroglobulin is present in the thyroid follicular cells. Thyroglobulin is a precursor of thyroid hormones and nearly all thyroid follicular carcinomas stain for thyroglobulin. Poorly differentiated carcinomas and non-thyroid adenocarcinomas do not stain for thyroglobulin. Anti-Thyroglobulin antibody clone JGN3 is a useful tool for identification of papillary and follicular thyroid carcinomas. Moreover, a panel of Anti-Thyroglobulin and Anti-Calcitonin is useful for identifying medullary thyroid carcinomas, whereas a panel of Anti-Thyroglobulin and Anti-TTF1 is useful for distinguishing between primary thyroid and lung neoplasms.
  • Thyroid adenoma with accumulation of throglobulin positive masses.
    Thyroid adenoma with accumulation of throglobulin positive masses.
    Thyroglobulin negative anaplastic thyroid carcinoma.
    Thyroglobulin negative anaplastic thyroid carcinoma.
    Follicular thyroid carcinoma with luminal throglobulin staining.
    Follicular thyroid carcinoma with luminal throglobulin staining.
    Papillary thyroid carcinoma with mosaic-like cytoplasmic staining.
    Papillary thyroid carcinoma with mosaic-like cytoplasmic staining.