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> CACNB3 antibody - C-terminal region

CACNB3 antibody - C-terminal region

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Referentie AI10148

Formaat : 100ug

Merk : Abcepta

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  • WB - CACNB3 antibody - C-terminal region AI10148
    CACNB3 antibody - C-terminal region (AI10148) in Human Jurkat cells using Western Blot
    WB Suggested Anti-CACNB3 Antibody Titration: 2.5μg/ml
    ELISA Titer: 1:62500
    Positive Control: Jurkat cell lysate
    CACNB3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P54284
Other Accession P54284, NP_000716, NM_000725
Reactivity Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Rat, Pig, Dog, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 53 kDa
Additional Information
Gene ID 784
Alias Symbol CAB3, CACNLB3
Other Names Voltage-dependent L-type calcium channel subunit beta-3, CAB3, Calcium channel voltage-dependent subunit beta 3, CACNB3, CACNLB3
Target/Specificity The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-CACNB3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCACNB3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CACNB3
Synonyms CACNLB3 {ECO:0000303|PubMed:7557998}
Function Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:8119293). Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity). Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity).
Cellular Location Cytoplasm.
Tissue Location Expressed mostly in brain, colon and ovary.