CCND3
Referentie AVARP03038_P050
Formaat : 100ul
Merk : Aviva Systems Biology
Neem contact op met een lokale distributeur :
Telefoonnummer : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for anti-CCND3 (AVARP03038_P050) antibody |
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| Publications | Discovery of Human-Similar Gene Fusions in Canine Cancers. Cancer Res. 77, 5721-5727 (2017). 28883003 |
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| Tested Species Reactivity | Human, Mouse |
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Sheep |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human CCND3 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Sheep: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: CQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-CCND3 (AVARP03038_P050) antibody is Catalog # AAP30245 (Previous Catalog # AAPP00415) |
| Sample Type Confirmation | CCND3 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Reference | Pruneri,G., et al., (2004) Int. J. Cancer 112 (1), 71-77 |
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| Gene Symbol | CCND3 |
| Gene Full Name | Cyclin D3 |
| NCBI Gene Id | 896 |
| Protein Name | G1/S-specific cyclin-D3 |
| Description of Target | CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. |
| Uniprot ID | P30281 |
| Protein Accession # | NP_001751 |
| Nucleotide Accession # | NM_001760 |
| Protein Size (# AA) | 292 |
| Molecular Weight | 33kDa |
| Protein Interactions | POLR3GL; TFIP11; CDKN1A; CDK6; CDK4; CDK5; MCM10; CDKN1B; CDK2; CDK11B; FAS; SIL1; EIF3K; ATF5; VDR; MAPK6; NME1; MYB; GC; ETV1; RBL2; POLD1; CDK14; APP; RB1; UBC; PPP1CC; PPP1CB; PPP1CA; NCOA2; MAF1; NPDC1; DMTF1; CRABP2; RARA; DTNBP1; AKAP8; EFEMP2; CAS |
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What is the species homology for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Sheep".
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How long will it take to receive "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "CCND3 Antibody - C-terminal region (AVARP03038_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?
This target may also be called "" in publications.
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What is the shipping cost for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
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What is the guarantee for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "33kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CCND3 Antibody - C-terminal region (AVARP03038_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CCND3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CCND3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CCND3"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CCND3"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CCND3"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CCND3"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.