Ephrin B (Ser300) Polyclonal Antibody, PE-Cy5 Conjugated
Referentie bs-3128R-PE-Cy5
Formaat : 100ul
Merk : Bioss
Ephrin B (Ser300) Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Reactivity
Overview | |
Catalog # | bs-3128R-PE-Cy5 |
Product Name | Ephrin B (Ser300) Polyclonal Antibody, PE-Cy5 Conjugated |
Applications | WB |
Reactivity | Human, Mouse, Rat, Bovine |
Specifications | |
Conjugation | PE-Cy5 |
Host | Rabbit |
Source | KLH conjugated synthetic phosphopeptide derived from human Ephrin B around the phosphorylation site of Ser300 |
Modification Site | Ser300 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 1947 |
Synonyms | Ephrin B phospho Y330; p-Ephrin B phospho Y330; CEK5 ligand; EFNB1; ELK L; EphrinB; Ephrin-B; ELK ligand; ELKL; EPH related receptor tyrosine kinase ligand 2; Ephrin B Precursor; Ephrin B1; Ephrin B2; LERK 2; LERK2; EFNB2_HUMAN. |
Background | Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase. |
Application Dilution | |
WB | 1:300-5000 |