Reagentia en instrumenten voor immunologie, celbiologie en moleculaire biologie.

Epstein-Barr Virus (LMP-1)(CS1), 0.2mg/mL

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Referentie BNUB1741-100

Formaat : 100uL

Neem contact op met een lokale distributeur :

Telefoonnummer : +1 850 650 7790

Merk : Biotium

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Neem contact op met een lokale distributeur :

Telefoonnummer : +1 850 650 7790

Antibody number	#1741
Antibody reactivity (target)	Epstein-Barr Virus
Antibody type	Primary
Host species	Mouse
Clonality	Monoclonal
Clone	CS1
Isotype	IgG1, kappa
Molecular weight	60 kDa
Synonyms	EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1; Human Herpesvirus 4 (HHV4)
Human gene symbol	Not Applicable
Entrez gene ID	Not Applicable
SwissProt	Not Applicable
Unigene	Not Applicable
Immunogen	Recombinant fusion protein containing the sequence of bacterial beta-galactosidase and the carboxyl half of EBV-encoded LMP
Antibody target cellular localization	Nucleus
Species reactivity	EBV
Expected antibody applications	IHC (frozen) (published for clone), IHC (FFPE) (published for clone), IP (published for clone), WB (published for clone)
Antibody application notes	ELISA: For coating, purchase antibody without BSA; Western blot 1-2 ug/mL; Optimal dilution for a specific application should be determined., Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
Positive control	EBV-infected cells. Tissues.
Shipping condition	Room temperature
Storage Conditions	Store at 2 to 8 °C, Protect fluorescent conjugates from light, Note: store BSA-free antibodies at -10 to -35 °C
Regulatory status	For research use only (RUO)
Antibody/conjugate formulation	Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA, Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide
Shelf life	Guaranteed for at least 24 months from date of receipt when stored as recommended
Product origin	Product may contain either bovine serum albumin (BSA) from bovine serum (Bos taurus), or recombinant BSA produced in Chinese hamster ovary cells. Inquire for the specific lot.

Product Description

This antibody is a mixture of four different monoclonal antibodies. This antibody is specific to 60 kDa latent membrane protein (LMP-1) encoded by the BNLF1 gene of the EBV. Each clone reacts with different epitopes on the hydrophilic C-terminus of the cytoplasmic domain of LMP-1. This antibody stains strongly with EBV-positive lymphoblastoid cell lines and EBV infected B cell immunoblasts in infectious mononucleosis. EBV, also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness.

Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the

CF® Dye Brochure

for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Stock status: Because Biotium offers a large number of antibody and conjugation options, primary antibody conjugates may be made to order. Typical lead times are up to one week for CF® dye and biotin conjugates, and up to 2-3 weeks for fluorescent protein and enzyme conjugates. Please email

info@clinisciences.com

to inquire about stock status and lead times before placing your order.

Catalog number key for antibody number 1741, Anti-Epstein-Barr Virus (CS1)

Antibody # prefix	Conjugation	Ex/Em (nm)	Laser line	Detection channel	Dye Features
BNC04	CF®405S	404/431	405	DAPI (microscopy), AF405	CF®405S Features
BNC88	CF®488A	490/515	488	GFP, FITC	CF®488A Features
BNC68	CF®568	562/583	532, 561	RFP, TRITC	CF®568 Features
BNC94	CF®594	593/614	561	Texas Red®	CF®594 Features
BNC40	CF®640R	642/662	633-640	Cy®5	CF®640R Features
BNC47	CF®647	650/665	633-640	Cy®5	CF®647 Features
BNC74	CF®740	742/767	633-685	775/50	CF®740 Features
BNCB	Biotin	N/A	N/A	N/A
BNUB	Purified	N/A	N/A	N/A
BNUM	Purified, BSA-free	N/A	N/A	N/A

Alexa Fluor, Pacific Blue, Pacific Orange, and Texas Red are trademarks or registered trademarks of Thermo Fisher Scientific; Cy is a registered trademark of Cytiva; IRDye, LI-COR, and Odyssey are registered trademarks of LI-COR Bioscience.

References

Note: References for this clone sold by other suppliers may be listed for expected applications.

J Exp Med (1993) 177: 339-349. (IHC, frozen; WB; mix of clones CS1-4)
J Clin Pathol (1995) 48:438-442. (IHC, FFPE; mix of clones CS1-4)
EMBO J (1999)18:3064-3073. (IP; mix of clones CS1-4)