Euonymus europaeus (EEL/EEA)

Affinity purified Euonymus europaeus lectin or agglutinin (EEL/EEA) is composed with most of the subunits that appear to consist of two chains linked by disulfide bonds. EEL consists of six closely related lectins (isoforms). EEL is identified for its erythrocyte agglutinating properties and specificity for blood groups B and H. It has a stronger binding of the H trisaccharide over the B trisaccharide, but has a general pattern of interacting with both B and H blood groups and alpha-mannose-terminated saccharides. EEL has a preferential recognition of terminal alpha-fucose residues in H and B blood group-related carbohydrates. This lectin binds to endothelial cells from human and non-human sources and recognizes carbohydrate structures on the surface of stimulated murine peritoneal lymphoid cells. See other EEL/EEA conjugates.||Source:|Spindle tree||Blood Specificity:|O (–SA), B||Sugar Specificity:|Galalpha; 3Gal||Inhibitory Carbohydrate:|Lactose||Divalent Ions:|Ca++, Zn++||Storage and Stability:|Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C.