Human IL-10 ELISpot Pair, 10 x 96-well

Referentie EA101813

Formaat : 10x96wells

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Human IL-10 ELISpot Pair, 10 x 96-well

Specifications
Product Data
ACCN NM_000572
Assay Type Enzyme-Linked ImmunoSpot (ELISpot)
Assay Type Sandwich
Background The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2011]
Components ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples.
Cross Reactivity No cross reactivity with other human cytokines. Cross reactivity with simian IL-10. No cross reactivity with viral IL-10.
Format 10 x 96-well
Gene Symbol IL10
Locus ID 3586
Signal Colorimetric
Species Human
Specificity Recognizes natural human IL-10
Target Symbol IL10
Description Human IL-10 ELISpot Pair, 10 x 96-well
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