Human Proteasome subunit alpha type 6 (PSMA6) activation kit by CRISPRa
Referentie GA103856
Formaat : 1kit
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Human Proteasome subunit alpha type 6 (PSMA6) activation kit by CRISPRa
SKU
GA103856
PSMA6 CRISPRa kit - CRISPR gene activation of human proteasome subunit alpha 6
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | PSMA6 |
| Locus ID | 5687 |
| Components | GA103856G1, Proteasome subunit alpha type 6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103856G2, Proteasome subunit alpha type 6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103856G3, Proteasome subunit alpha type 6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001282232, NM_001282233, NM_001282234, NM_002791, NR_104110 |
| UniProt ID | P60900 |
| Synonyms | IOTA; p27K; PROS27 |
| Summary | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN409976 | PSMA6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.