B1543-200mg | Mubritinib (TAK 165) [366017-09-6] Clinisciences

Background

Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM; no activity to EGFR, FGFR, PDGFR, JAK1, Src and Blk.

Storage	Store at -20°C
M.Wt	468.47
Cas No.	366017-09-6
Formula	C₂₅H₂₃F₃N₄O₂
Solubility	insoluble in H2O; ≥76.9 mg/mL in DMSO with gentle warming; ≥3.09 mg/mL in EtOH with gentle warming and ultrasonic
Chemical Name	4-[[4-[4-(triazol-1-yl)butyl]phenoxy]methyl]-2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,3-oxazole
SDF	Download SDF
Canonical SMILES	C1=CC(=CC=C1CCCCN2C=CN=N2)OCC3=COC(=N3)C=CC4=CC=C(C=C4)C(F)(F)F
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Purity = 99.80%