Formaat : 50mg
Telefoonnummer : +1 850 650 7790
| Molecular Formula | C14H24N2O4 |
| Molecular Weight | 284.35 |
| CAS Numbers | 187227-45-8 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | 50 mg/mL in water |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4R-(acetylamino)-5S-amino-3R-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid |
| InChl Key | NENPYTRHICXVCS-YNEHKIRRSA-N |
| InChl Code | InChI=1S/C14H24N2O4/c1-4-10(5-2)20-12-7-9(14(18)19)6-11(15)13(12)16-8(3)17/h7,10-13H,4-6,15H2,1-3H3,(H,16,17)(H,18,19)/t11-,12+,13+/m0/s1 |
| SMILES Code | O=C(O)C1=C[C@H]([C@@H]([C@H](C1)N)NC(C)=O)OC(CC)CC |
| References | 1) Li W, et al. Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071. Antimicrob Agents Chemother. 1998 Mar;42(3):647-53. 2) Ghosh GC, et al. Oseltamivir carboxylate, the active metabolite of oseltamivir phosphate (Tamiflu), detected in sewage discharge and river water in Japan. Environ Health Perspect. 2010 Jan;118(1):103-7. 3) Ferraris O, et al. Sensitivity of influenza viruses to zanamivir and oseltamivir: a study performed on viruses circulating in France prior to the introduction of neuraminidase inhibitors in clinical practice. Antiviral Res. 2005 Oct;68(1):43-8. |
Active metabolite of oseltamivir phosphate (Tamiflu)
