PE Conjugated Anti-TCR gamma/delta Monoclonal Antibody (Clone:V65)

Referentie 30-2308-0.1

Formaat : 0,1mg

Merk : Abeomics

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PE Conjugated Anti-TCR gamma/delta Monoclonal Antibody (Clone:V65)

0.1 mg
 



Amount : 0.1 mg
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : Plcg1
Gene ID : 25738
Uniprot ID : P10686
Alternative Name : Plcg1
Immunogen Information : TCR alpha/beta-negative CD3-positive rat T cell hybridoma III.89.1.4 line

The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.

Subcellular location: Cell projection, Cell projection
Post transnational modification: Ubiquitinated by CBLB in activated T-cells.
BioGrid: 247766. 3 interactions.
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