AG Scientific
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AG Scientific is gespecialiseerd in secundaire metabolieten afkomstig van fermentatie. De meeste van hun producten zijn antibiotica voor genselectie, maar de catalogus bevat ook antimicrobiële, antischimmel, antikanker, antivirale, antiparasitaire en immunosuppressieve reagentia.
Antibiotica:
AG Scientific, Inc. heeft een serie antibiotische screeningsmiddelen ontwikkeld, waaronder Blasticidin S, G-418, Puromycine, Gentamycine, Kanamycine, Ampicilline, Streptomycine en Carbenicilline.
Meer recent werkt AG Scientific samen met farmaceutische klanten die CRISPR-technologie gebruiken.
Antikanker
De catalogus bevat secundaire metabolieten op het gebied van kanker zoals rapamycine, FK-506, cyclosporine A.
Website: www.agscientific.com
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![Cationic lipids / polymers](https://www.clinisciences.com/nl/upload/thumbs/copie-de-bandeau3-gf4yz-8pScZhPc-4e77f5.png)
Cationic lipids / polymers
Cationic lipids and polymers are widely used as transfection reagents in molecular biology, allowing for the introduction of exogenous nucleic acids into cells. These reagents form complexes with negatively charged genetic material, such as plasmid DNA or siRNA, which can then enter cells and release the genetic material for integration or transient expression. Cationic lipids and polymers offer several advantages over other methods of gene delivery, including ease of use, cost-effectiveness, and low immunogenicity.
They are also applicable to a wide range of cell types, including primary and difficult-to-transfect cells. However, their low transfection efficiency and limited cargo capacity remain significant challenges, prompting ongoing research into improving their performance.
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- Buffers and reagents 2