CANDOR Bioscience
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CANDOR ontwikkelt, produceert en distribueert een uitgebreide selectie hoogwaardige oplossingen voor immunoassays. CANDOR biedt meer dan 50 verschillende producten, waaronder optimizers, blockers, stabilisatoren en bufferoplossingen voor immunoassays. Door deze oplossingen te gebruiken kan de betrouwbaarheid van de resultaten worden verbeterd, kan de assay worden vereenvoudigd en kunnen procestijden worden verkort. Meer dan 850 klanten in 50 landen gebruiken CANDOR producten en profiteren van de expertise van CANDOR in assayontwikkeling en monstermetingen. Website : www.candor-bioscience.de
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Optimization buffers
Why do you need optimization?
- If you have false positive or negative results.
- If you have a specific signal lack due to too much background noise.
Problems with immunoassay results are frequent, with more than 80% of the tests being affected by different types of problems that are independent of the manipulator's level of experience.
These problems can have several sources:
- Matrix Effects
- Cross-reactivity
- Non-specific connections
- HAMAs (human anti-mouse antibodies) or other heterophilic antibodies
- The endogenous proteins present in the tested samples
The perfect solution for interference problems in immunoassays should remove weak to medium affinities without affecting strong affinities.
Optimization solutions are a class of solutions for advantageous and multifunctional immunoassays.
They are different from other diluents and buffers. We offer a buffer that combines several functionalities of diluents in a product and that is not just a dosage diluent. In addition, it can reduce HAMA interference and helps avoid matrix effects. Another product allows one-step incubation analyzes without compromising the reliability of the results. This is due both to the optimization and stabilization properties of the solution. The casein-based surface blocker is also part of the class of optimizers. The blocking solution has exceptional blocking characteristics combined with reduced background noise and high sensitivity of the immunoassay.
