AG Scientific
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AG Scientific is gespecialiseerd in secundaire metabolieten afkomstig van fermentatie. De meeste van hun producten zijn antibiotica voor genselectie, maar de catalogus bevat ook antimicrobiële, antischimmel, antikanker, antivirale, antiparasitaire en immunosuppressieve reagentia.
Antibiotica:
AG Scientific, Inc. heeft een serie antibiotische screeningsmiddelen ontwikkeld, waaronder Blasticidin S, G-418, Puromycine, Gentamycine, Kanamycine, Ampicilline, Streptomycine en Carbenicilline.
Meer recent werkt AG Scientific samen met farmaceutische klanten die CRISPR-technologie gebruiken.
Antikanker
De catalogus bevat secundaire metabolieten op het gebied van kanker zoals rapamycine, FK-506, cyclosporine A.
Website: www.agscientific.com
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N-Glycolylneuraminic Acid
N-Glycolylneuraminic acid (Neu5Gc), a sialic acid variant, has emerged as a molecule of profound significance in the realms of immunology, cell biology, and molecular biology.
In immunology, Neu5Gc intricately connects with immune recognition and response. Its incorporation into glycoproteins on cell surfaces can trigger immune reactions, influencing processes such as inflammation and autoimmunity. Understanding Neu5Gc's immunological impact is critical for unraveling its role in various pathological conditions.
In cell biology, Neu5Gc contributes significantly to glycobiology, influencing cellular interactions and signaling. Its incorporation into glycoconjugates impacts cell adhesion, migration, and communication. Exploring the dynamics of Neu5Gc in cellular processes provides insights into its broader cellular implications.
At the molecular level, Neu5Gc influences various biological pathways and molecular interactions. Studies link Neu5Gc to cancer progression, inflammation, and vascular diseases, shedding light on its involvement in disease pathogenesis. Unraveling these molecular connections offers avenues for targeted therapeutic interventions.