APExBIO Technology
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ApexBio is een vooraanstaande leverancier van peptiden en laboratoriumreagentia voor biologisch onderzoek. ApexBio heeft een brede productlijn op onderzoeksgebieden zoals apoptose, epigenetica, kankerbiologie, enzovoort. Apexbio levert ook diensten op maat, waaronder peptidesynthese, antilichaamproductie en assayontwikkeling. | ||
Phytopathology reagents - Polymyxin B
Polymyxin B is a member of the polymyxin group of antibiotics, obtained from different strains of Bacillus polymyxa and related species.
Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic. All gram-positive bacteria, fungi, and the gram-negative cocci, are resistant.
Polymixin B acts against microorganisms by binding to and interfering with the permeability of the cytoplasmic membrane. After binding to lipopolysaccharide (LPS) in the outer membrane of Gram-negative bacteria, polymyxins disrupt both the outer and inner membranes. The hydrophobic tail is important in causing membrane damage, suggesting a detergent-like mode of action.
Polymixin B can be used with a basal medium and additional antibiotics to select specific microorganisms like Acidovorax avenae and Ralstonia solanacearum for phytopathology.
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