Canvax Biotech
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Canvax is a leading manufacturer and supplier of the most innovative solutions, kits and R&D Reagents inside Molecular Biology fields. Since its foundation in 2001, Canvax offers reliable, cost-effective and easy-to-use innovative tools for research. Based in Córdoba (Spain), since its beginning it has focused on R&D of multiplex high throughput platforms (HTS) for Drug discovery and Diagnostic applied biosensors. Over a decade later, Canvax is a worldwide leading expert in GPCR expression in heterologous cells, with important patents and exclusive know-how. Canvax prides itself to be the first company to get an unprecedented milestone that could revolutionize the Diagnostics sector: Canvax established stable high-level expression of odour GPCRs into heterologous cell lines in 2014. This key milestone, that could be applied in diagnostic, perfume and cosmetic industry, are being employed to obtain a molecular nose, a sensitive and non-invasive diagnostic molecular device for early detection of cancer, as the nose of trained dogs do. Thanks to this project, Canvax was awarded, in 2013, with the largest Public & Private Contract for Pre competitive Technology Development in Spanish history. Website : www.lifescience.canvaxbiotech.com | ||
Related reagents - Detection of cell contamination
Mycoplasma and bacterial contamination is a major concern for research laboratories (e.g. in cell biology) or biopharmaceutical laboratories (production of vaccines, monoclonal antibodies, etc.).
Mycoplasmas are the smallest self-producing microorganisms and can reproduce in extracellular space. Although they are mostly harmless to humans, other host animals and plants, some species can cause disease in humans. In particular, 6 species are a frequent cause of contamination in continuous cell lines and primary cells. Because of their size, mycoplasma are not detectable (e.g. under the microscope) and yet they profoundly alter cell cultures (metabolism, cell growth, pH, viability, membrane transport).
The main source of mycoplasma contamination is other infected cell cultures as well as culture media, reagents (fetal bovine serum, trypsin, etc.) and laboratory personnel.
Mycoplasma contaminations can cost money, time and reputation, compromise research results or impact the safety of biologic therapies. Effective strategies against mycoplasma contaminations are prevention, early detection, removal of infected material, or disposal of mycoplasma.
Early detection of bacteria in cell cultures is the only reasonable solution and the only control measure against a common problem for life science laboratories: bacterial contaminations in cell cultures.
Up to 5% of all cell cultures are contaminated with bacteria but show no visual signs of bacterial contamination, such as turbidity, sudden change in the colour of the medium (phenol red) or microscopic particles. In addition, bacteria may show resistance or lack of sensitivity to standard antibiotics (e.g. penicillin/streptomycin) and have a direct impact on cell metabolism, growth and differentiation.
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