Biorbyt
Products for advancing your discoveries From antibodies to proteins, biochemicals to ELISA kits, Biorbyt's high quality research products are available for you to enable world class research and contribution to a deeper understanding of life sciences.
A comprehensive catalog of life science research products covering the areas of Neuroscience, Signal transduction, Cell Biology, Cancer Metabolism, Cardiovascular and others
Product range :
Choose from over 100,000 primary antibodies and over 2,000 secondary antibodies. Monoclonals and polyclonals tested in a number of applications - WB, ELISA, IHC, FACS and many more.
Choose from over 7,000 proteins and over 400 active proteins. All of our proteins have been validated for use in ELISAs, WB and IHC-P
We have over 10,000 biochemicals for use in your research.
We have over 2,000 ELISA kits covering many research areas . Each kit comes with a fully detailed protocol and examples of expected results.
Website : https://www.biorbyt.com/
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SARS-CoV-2 - Leflunomide - Therapeutic Candidates
Leflunomide is an immunosuppressant used as a disease-modifying drug for rheumatoid arthritis and psoriatic arthritis. Immunosuppressants are drugs that decrease the immune system and chronic inflammation of the joints. Leflunomide has an anti-rheumatic effect with a slow onset of action. It works by stabilizing the overactivity of immune system cells that cause inflammation of the joints. To do this, leflunomide inhibits the mitochondrial enzyme dihydroorotate dehydrogenase (DHOH) which plays a key role in the synthesis of uridine monophosphate (rUMP), necessary for the synthesis of DNA and RNA.
A study to examine the tolerability of high doses of leflunomide in patients with COVID-19 who are not yet hospitalized, but who have risk factors for disease progression and complications, has begun. In vitro studies have shown the antiviral effects of leflunomide against CoV-2-SARS. The hypothesis of this study is that targeting high-risk patients earlier in disease progression and a higher dose of leflunomide are necessary to see an improvement in disease outcome with COVID-19.
Resultaat van uw zoeken : 21 product gevonden
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RUOCE / IVD
- Biochemicals 21
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