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![SARS-CoV-2 - Envelope protein (Protein E) - Antigens (proteins and peptides)](https://www.clinisciences.com/nl/upload/thumbs/sars-cov-2-antigen-6t55ch-8b35cf.jpg)
SARS-CoV-2 - Envelope protein (Protein E) - Antigens (proteins and peptides)
Coronavirus 2019 disease (COVID-19), formerly known as Acute Respiratory Illness 2019-nCoV, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The envelope protein, or protein E, is a small 100-residue polypeptide that contains at least one helical transmembrane domain α and a group of 2-3 juxtamembrane cysteines. It is involved in several processes of the virus life cycle, such as assembly, budding, envelope formation and pathogenesis. Protein E has membrane permeabilizing activity, which may justify in vitro inhibition of the ion channel activity of some synthetic coronavirus E proteins, as well as viral replication. It acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. It also plays a role in the induction of apoptosis, activates the NLRP3 inflammasome of the host resulting in overproduction of IL-1 beta.
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RUOCE / IVD
- Unconjugated 12
- virus 3
- Protein/peptide 17
- virus 2
- WB 9
- ELISA 5
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MBS8122440-0,1mg
0.1mg
MBS8122440-5x0,1mg
5x0.1mg
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