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> Anti-ATP2A1 antibody (548-597 aa)

Anti-ATP2A1 antibody (548-597 aa)

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Referentie NB-22-5616-50

Formaat : 50ug

Merk : Neo Biotech

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Telefoonnummer : +1 850 650 7790

  • Western blot analysis of lysates from HT-29, A549, and NIH/3T3 cells, using ATP2A1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using SERCA1 Polyclonal Antibody diluted at 1：2000

General Info

Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat/Salamander/Pig
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Sarcoplasmic/endoplasmic reticulum calcium ATPase 1-ATPase 1 ATPase (548-597 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol: ATP2A1
Gene ID: 487
Uniprot ID: AT2A1_HUMAN
Immunogen Region: 548-597 aa
Specificity: SERCA1 Polyclonal Antibody detects endogenous levels of SERCA1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ATP2A1 at the amino acid range 548-597

Description

Function Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Protein Name Sarcoplasmic/Endoplasmic Reticulum Calcium Atpase 1
Serca1
Sr Ca(2+-Atpase 1
Calcium Pump 1
Calcium-Transporting Atpase Sarcoplasmic Reticulum Type - Fast Twitch Skeletal Muscle Isoform
Endoplasmic Reticulum Class 1/2 Ca(2+ Atpase
Database Links Reactome: R-HSA-1912420
Reactome: R-HSA-418359
Reactome: R-HSA-5578775
Reactome: R-HSA-936837
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Sarcoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Sarcoplasmic/Endoplasmic Reticulum Calcium Atpase 1 antibody
Anti-Serca1 antibody
Anti-Sr Ca(2+-Atpase 1 antibody
Anti-Calcium Pump 1 antibody
Anti-Calcium-Transporting Atpase Sarcoplasmic Reticulum Type - Fast Twitch Skeletal Muscle Isoform antibody
Anti-Endoplasmic Reticulum Class 1/2 Ca(2+ Atpase antibody
Anti-ATP2A1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance