General Info
Host: | Rabbit |
Applications: | ELISA/IP/WB |
Reactivity: | Cat/Human/Monkey/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-F13A1 (1-50) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.55-0.75 µg/µl |
Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:150 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
Gene Symbol: | F13A1 |
Gene ID: | 2162 |
Uniprot ID: | F13A_HUMAN |
Immunogen Region: | 1-50 |
Immunogen: | Synthetic peptide taken within amino acid region 1-50 on human factor XIII A subunit protein. |
Description
Post Translational Modifications | The activation peptide is released by thrombin. |
Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
Protein Name | Coagulation Factor Xiii A Chain Coagulation Factor Xiiia Protein-Glutamine Gamma-Glutamyltransferase A Chain Transglutaminase A Chain |
Database Links | Reactome: R-HSA-114608 Reactome: R-HSA-140875 Reactome: R-HSA-6785807 |
Cellular Localisation | Cytoplasm Secreted Secreted Into The Blood Plasma Cytoplasmic In Most Tissues But Also Secreted In The Blood Plasma |
Alternative Antibody Names | Anti-Coagulation Factor Xiii A Chain antibody Anti-Coagulation Factor Xiiia antibody Anti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibody Anti-Transglutaminase A Chain antibody Anti-F13A1 antibody Anti-F13A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance