Anti-SLC29A1 antibody (200-300)

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	SLC29A1
Gene ID:	2030
Uniprot ID:	S29A1_HUMAN
Immunogen Region:	200-300
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC29A1 (NP_001071645.1).
Immunogen Sequence:	ELSESAFGYFITACAVIILT IICYLGLPRLEFYRYYQQLK LEGPGEQETKLDLISKGEEP RAGKEESGVSVSNSQPTNES HSIKAILKNISVLAFSVCFI F

Tissue Specificity	Expressed in testis at the blood-testis barrier (at protein level). Detected in erythrocytes (at protein level). Expressed at relatively high levels in cerebral cortex, particularly the frontal and parietal lobes, and the thalamus and basal ganglia (at protein level). In the midbrain expressed at moderate levels, whereas in the other areas of the brainstem, namely medulla and pons, cerebellum and the hippocampus expressed at lower amounts when compared to the other brain regions (at protein level). Expressed in Langerhans cells and lymphocytes in the pancreas (at protein level). Expressed in kidney, in polarized renal epithelial cells. Expressed in adipose tissues. Expressed in placenta. Expressed in small intestine.
Post Translational Modifications	Glycosylated.
Function	Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier. Regulates inosine levels in brown adipocytes tissues (BAT) and extracellular inosine levels, which controls BAT-dependent energy expenditure.
Protein Name	Equilibrative Nucleoside Transporter 1 Hent1 Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter Equilibrative Nbmpr-Sensitive Nucleoside Transporter Es Nucleoside Transporter Nucleoside Transporter - Es-Type Solute Carrier Family 29 Member 1
Database Links	Reactome: R-HSA-83936 Reactome: R-HSA-9748787 Reactome: R-HSA-9755088
Cellular Localisation	Basolateral Cell Membrane Multi-Pass Membrane Protein Apical Cell Membrane Cell Membrane Localized To The Basolateral Membrane Of Sertoli Cells Localized To The Cell Membrane Of Erythrocytes
Alternative Antibody Names	Anti-Equilibrative Nucleoside Transporter 1 antibody Anti-Hent1 antibody Anti-Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter antibody Anti-Equilibrative Nbmpr-Sensitive Nucleoside Transporter antibody Anti-Es Nucleoside Transporter antibody Anti-Nucleoside Transporter - Es-Type antibody Anti-Solute Carrier Family 29 Member 1 antibody Anti-SLC29A1 antibody Anti-ENT1 antibody

Information sourced from Uniprot.org

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