Bax antibody
Referentie GTX16143-125ug
Formaat : 125ug
Merk : GeneTex
Host | Sheep |
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Clonality | Polyclonal |
Isotype | IgG |
Application | IP |
Reactivity | Human |
Package | 125 μg |
View product citations for antibody GTX16143 on CiteAb
APPLICATION
Application Note
IP: Use at an assay dependent dilution. Is unsuitable for WB. Will not detect denatured protein. Optimal dilutions/concentrations should be determined by the end user.
Calculated MW
21 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.08% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide: LTTAPAPPSLPPATPLGPWAFWSRSQWC, corresponding to amino acids 172-199 of Human beta Bax.
Purification
Protein G purified
This antibody is provided as a 0.2 μm sterile filtered solution.
This antibody is provided as a 0.2 μm sterile filtered solution.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
BCL2 associated X, apoptosis regulator , BCL2L4
Cellular Localization
Cytoplasm
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
Database
REVIEW
SDS | |
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PBS.pdf | |
Sodium Azide.pdf |