CD32 (Fcg Receptor II) (Biotin)

Referentie C2384-01B-100ug

Formaat : 100ug

Merk : US Biological

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C2384-01B CD32 (Fcg Receptor II) (Biotin)

Clone Type
Polyclonal
Host
mouse
Source
human
Swiss Prot
P12318, P31994, P31995
Isotype
IgG1
Grade
Affinity Purified
Applications
FC
Crossreactivity
Ca Hu Mk
Shipping Temp
Blue Ice
Storage Temp
-20°C

CD32 is a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets.||Applications:|Suitable for use in Flow Cytometry. Other applications not tested.||Recommended Dilutions:|Flow Cytometry: Use 10ul to label 10e6 cells or 100ul whole blood. |Optimal dilutions to be determined by the researcher.||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Mab|Isotype: IgG1|Clone No: 3H1232 (AT10)|Host: mouse|Source: human|Concentration: As reported |Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.|Purity: Purified by Protein A affinity chromatography.|Immunogen: K562 cell line.|Specificity: Recognizes human CD32 at ~40kD. |Species Crossreactivity: canine, Rhesus monkey and porcine.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
K562 cell line.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human CD32 at ~40kD. |Species Crossreactivity: canine, Rhesus monkey and porcine.
References
1. Greenman, J. et al. (1991). Characterisation of a new monoclonal anti-Fc gamma RII antibody, AT10, and its incorporation into a bispecific F(ab')2 derivative for recruitment of cytotoxic effectors. Mol. Immunol. 28: 1243-1254.