Specifications

Product Data
Clone Name	CEA-Y1
Applications	ELISA, WB
Recommended Dilution	ELISA: In combination with matched detection antibody Clone CEA-Y2 (Cat.-No AM09248PU-N), this antibody can be used as capture antibody in sandwich ELISA for quantitative detection of CEA.  Suggested Coating Dose: 2 µg/ml.  Western Blot: 25 ng/ml antigen can be detected using 100 ng/ml antibody.
Reactivities	Human
Host	Mouse
Isotype	IgG1
Clonality	Monoclonal
Immunogen	Human Carcinoembryonic Antigen (CEA), which was isolated from Human cancer tissue.
Specificity	Recognizes Carcinoembryonic Antigen CEA No detectable cross-reaction with Human normal serum proteins.
Formulation	0.01M PBS, pH 7.0 without preservatives. State: Aff - Purified State: Lyophilized purified Ig fraction.
Reconstitution Method	Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
Purification	Affinity Chromatography on Protein G.
Conjugation	Unconjugated
Storage	Upon receipt, store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Gene Name	carcinoembryonic antigen related cell adhesion molecule 5
Database Link	Entrez Gene 1048 Human UniProt ID P06731
Background	Carcinoembryonic Antigen (CEA) is a 180-200 KD glycoprotein expressed at high level in the epithelial cells of the embryonic colon. The expression is stopped after birth. CEA serum content is low in normal population and only slightly elevated in heavy smokers. Increased serum CEA level was found to associate with colorectal carcinoma, gastric carcinoma, pancreatic carcinoma, lung carcinoma, and breast carcinoma. However elevated CEA level does not necessarily indicate neoplastic conditions. CEA level is useful for monitoring tumour recurrence after surgical resection of carcinoma.
Synonyms	CEA, Carcinoembryonic antigen
Reference Data