Clevudine
Referentie M5526-10mg
Formaat : 10mg
Merk : AbMole Bioscience
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Telefoonnummer : +1 850 650 7790
All AbMole products are for research use only, cannot be used for human consumption.
Quality Control & Documentation
Biological Activity
Clevudine (L-FMAU) is a nucleoside analogue with unnatural L-configuration, which has strong anti-HBV activity, long half-life and low toxicity. Clevudine is a non-competitive inhibitor that binds not to viral DNA but to the polymerase.
Chemical Information
| Molecular Weight | 260.22 |
| Formula | C10H13FN2O5 |
| CAS Number | 163252-36-6 |
| Solubility (25°C) | 52 mg/mL in DMSO |
| Storage | Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] Tak WY, et al. Hepatol Int. A randomized, open-label study comparing low-dose clevudine plus adefovir combination therapy with clevudine monotherapy in naïve chronic hepatitis B patients.