Clinisciences > FHL1 Antibody - N-terminal region : Biotin
FHL1 Antibody - N-terminal region : Biotin
Referentie ARP31902_P050-Biotin
Formaat : 100ul
Merk : Aviva Systems Biology
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Datasheets/Manuals | Printable datasheet for anti-FHL1 (ARP31902_P050) antibody |
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Tested Species Reactivity | Human, Mouse |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | The immunogen is a synthetic peptide corresponding to a region of Human |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 92%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100% |
Peptide Sequence | Synthetic peptide located within the following region: SKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPK |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-FHL1 (ARP31902_P050) antibody is Catalog # AAP31902 (Previous Catalog # AAPP02702) |
Reference | Rice,K.L., (2008) Biochem. Biophys. Res. Commun. 367 (3), 707-713 |
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Gene Symbol | FHL1 |
Gene Full Name | Four and a half LIM domains 1 |
Alias Symbols | KYOT, SLIM, FCMSU, FHL-1, FHL1A, FHL1B, FLH1A, SLIM1, XMPMA, RBMX1A, RBMX1B, SLIM-1, SLIMMER |
NCBI Gene Id | 2273 |
Protein Name | Four and a half LIM domains protein 1 |
Description of Target | LIM proteins, named for 'LIN11, ISL1, and MEC3,' are defined by the possession of a highly conserved double zinc finger motif called the LIM domain.FHL1 contains 3 LIM zinc-binding domains. It may have an involvement in muscle development or hypertrophy.LIM proteins, named for 'LIN11, ISL1, and MEC3,' are defined by the possession of a highly conserved double zinc finger motif called the LIM domain.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Uniprot ID | Q6IB30 |
Protein Accession # | NP_001440 |
Nucleotide Accession # | NM_001449 |
Protein Size (# AA) | 280 |
Molecular Weight | 32kDa |
Protein Interactions | SUMO2; UBC; SRPK1; SMAD4; SMAD3; SMAD2; LMNA; CSNK1D; NRIP1; ESR1; HIVEP3; SMURF1; UBE2E2; STAT4; RING1; RBPJ; FHL1; KCNA5; PRNP; USP15; HHV8GK18_gp81; SP1; TXNIP; DEAF1; PDE4DIP; AKAP12; EED; HES1; DBN1; CBX4; FHL2; SRF; MYBPC1; |
Protein interactions
Name | # of Products |
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AKAP12 | 77 |
CBX4 | 52 |
DBN1 | 46 |
DEAF1 | 26 |
EED | 123 |
FHL2 | 120 |
HES1 | 107 |
HIVEP3 | 16 |
MYBPC1 | 8 |
PDE4DIP | 33 |
RBPJ | 42 |
RING1 | 63 |
SRF | 172 |
TXNIP | 11 |
UBC | 7030 |
Biological process
Name | # of Products |
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Cell differentiation | 490 |
Multicellular organismal development | 896 |
Muscle organ development | 83 |
Negative regulation of cell growth | 119 |
Negative regulation of G1/S transition of mitotic cell cycle | 5 |
Negative regulation of G2/M transition of mitotic cell cycle | 2 |
Organ morphogenesis | 132 |
Cellular components
Name | # of Products |
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Cytoplasm | 4549 |
Cytosol | 1868 |
Nucleus | 4914 |
Plasma membrane | 2678 |
Protein function
Name | # of Products |
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Metal ion binding | 5514 |
Molecular_function | 955 |
Protein binding | 12191 |
Zinc ion binding | 3721 |
Diseases
Name | # of Products |
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Cardiomyopathy | 211 |
Disease mutation | 5332 |
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