GFAP (Glial Fibrillary Acidic Protein) (FITC)
Referentie 214855-FITC-100ul
Formaat : 100ul
Merk : US Biological
214855-FITC GFAP (Glial Fibrillary Acidic Protein) (FITC)
Clone Type
PolyclonalHost
mouseSource
bovineSwiss Prot
P14136, P47819, P03995, Q28115Isotype
IgG2bGrade
Affinity PurifiedApplications
IHC RIA WBCrossreactivity
Bo Ca Ch Gp Hu Mo Po Rb Rt ShShipping Temp
Blue IceStorage Temp
-20°CGlial fibrillary acidic protein, or GFAP, a class III intermediate filament. During development of the central nervous system, GFAP distinguishes astrocytes from other glial cells. It is involved in various cellular functions, such as cell structure and movement, cell communication and the functioning of the blood-brain barrier. It also plays a role in mitosis by adjusting the filament network present in the cell.||Defects in GFAP are a cause of Alexander disease, a rare disorder of the central nervous system affecting mostly males. It is a progressive leukoencephalopathy resulting in mental and physical retardation, dementia, seizures and early death.||Applications: |Suitable for use in RIA, Western Blot, Immunohistochemistry. Other applications not tested.||Recommended Dilution:|Optimal dilutions to be determined by the researcher.||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. |Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.||Note: Applications are based on unconjugated antibody.