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Immunohistochemistry
Application

Immunohistochemistry

Immunohistochemical staining of human colon tissue with HSPD1 monoclonal antibody, clone LK2 (Cat # MAB6622).

  • Specifications

    Product Description

    Mouse monoclonal antibody raised against recombinant HSPD1.

    Immunogen

    Recombinant protein corresponding to human HSPD1.

    Host

    Mouse

    Reactivity

    Bovine, Chicken, Dog, Escherichia coli, Guinea pig, Hamster, Helicobacter pylori, Human, Monkey, Mouse, Nematoda, Pig, Plants, Rabbit, Rat, S. typhi, Yeast

    Specificity

    Detects an ~60KDa protein corresponding to the molecular mass of Hsp60 on SDS PAGE immunoblots.

    Form

    Liquid

    Isotype

    IgG1

    Recommend Usage

    Western Blot (0.25 ug/mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS (50% glycerol, 0.1 mM PMSF)

    Storage Instruction

    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot

    Immunohistochemistry

    Immunohistochemical staining of human colon tissue with HSPD1 monoclonal antibody, clone LK2 (Cat # MAB6622).

    Flow Cytometry

  • Gene Info — HSPD1

    Entrez GeneID

    3329

    Gene Name

    HSPD1

    Gene Alias

    CPN60, GROEL, HLD4, HSP60, HSP65, HuCHA60, SPG13

    Gene Description

    heat shock 60kDa protein 1 (chaperonin)

    Omim ID

    118190 605280

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq

    Other Designations

    P60 lymphocyte protein|chaperonin|heat shock 60kD protein 1 (chaperonin)|heat shock protein 65|mitochondrial heat shock 60kD protein 1 variant 1|mitochondrial matrix protein P1|short heat shock protein 60 Hsp60s1|spastic paraplegia 13 (autosomal dominant)

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