Human CD105 (ENG) activation kit by CRISPRa
Referentie GA101405
Formaat : 1kit
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Human CD105 (ENG) activation kit by CRISPRa
SKU
GA101405
ENG CRISPRa kit - CRISPR gene activation of human endoglin
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | ENG |
| Locus ID | 2022 |
| Components | GA101405G1, CD105 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101405G2, CD105 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101405G3, CD105 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_000118, NM_001114753, NM_001278138 |
| UniProt ID | P17813 |
| Synonyms | END; HHT1; ORW1 |
| Summary | This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN421699 | ENG - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.