Interferon gamma (IFNG) Mouse Monoclonal Antibody [Clone ID: #6]
CAT#: AM26465AF-N
Interferon gamma (IFNG) mouse monoclonal antibody, clone #6, Azide Free
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Specifications
Product Data | |
Clone Name | #6 |
Applications | Neutralize |
Recommended Dilution | Neutralizing activity: 3.95 x 103 (NU/ml). The apparent neutralizing effect of antibody against IFN-gamma may vary depending on cell types and growth conditions. The amounts of neutralized IFN-gamma activity by the serially diluted antibodies were measured under the condition stated in the protocol below. The diluted antibody at the dilution factor 3.95 x 10e3 may neutralize the 1 IU/ml (International Reference Unit) of IFN-gamma in the solution, that is, 1 NU/ml (arbitrary standardized neutralizing unit) of antibody may neutralize the 1 IU/ml of IFN-gamma activity in the solution. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified human IFN-gamma. |
Specificity | This antibody neutralizes IFN-gamma. |
Formulation | PBS containing 50% glycerol, pH 7.2. No preservative is contained. State: Azide Free State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein A agarose |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | interferon, gamma |
Database Link | |
Background | IFN-gamma, also known as type II interferon, is mainly produced in activated T lymphocytes and NK cells. It is involved in the regulation of nearly all phases of immune and inflammatory responses, such as the activation, growth, and differentiation of T cells, B cells, macrophages and also several other cell types, including endothelial cells and fibroblasts. IFN-gamma has antiviral and antiproliferative activities, it has also been shown to inhibit the proliferation of a variety of cells. Synthesis of IFN-gamma is upregulated by IL2, FGF basic and EGF. |
Synonyms | IFN-gamma, gamma IFN |
Note | This product was originally produced by MBL International. Protocol: Neutralization of IFN-gamma activity |
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