Narcissus pseudonarcissus (NPL/NPA)

Referentie 518598-5mg

Formaat : 5mg

Merk : US Biological

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518598 Narcissus pseudonarcissus (NPL/NPA)

Clone Type
Polyclonal
Grade
Affinity purified
Shipping Temp
Blue Ice
Storage Temp
-20°C

Narcissus pseudonarcissus lectin or agglutinin (NPL/NPA) is affinity purified composed of four subunits. It agglutinates rabbit erythrocytes but is non-reactive with human erythrocytes. NPA has an isoelectric point between pH 4.2 and pH 4.6 with a specific binding activity toward alpha-D-mannose, although studies have suggested that the purified lectin may have greater affinity for internal mannosyl residues than for nonreducing terminal units. A buffer washed column elutes the sugar alpha-methylmannoside. Human studies have found NPA to be nearly non-mitogenic, but it has been reported through an in vitro study that mitogenicity of NPA is age-related, with lymphoproliferative response of peripheral blood mononuclear cells (PBMC) in umbilical cord blood has a sevenfold increase than adult blood. NPA has also been found to be mitogenic for PBMC from lambs and not adult sheep.||Source:|Lent lily||Blood Specificity:|Rabbit Agglutinin||Sugar Specificity:|alpha-Mannose||Inhibitory Carbohydrate:|alpha-Methylmannoside||Divalent Ions:|None Required||Storage and Stability:|Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Applications
Source: Lent lily|Purity: Affinity purified|Form: Supplied as a lyophilized powder.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Form
Supplied as a lyophilized powder.
Purity
Affinity purified