- More Files
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Specifications
Product Description
PROC (Human) ELISA Kit is a competitive enzyme immunoassay for the quantitative measurement of human PROC.
Suitable Sample
Plasma, Serum
Sample Volume
25 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
0.094 to 6 ug/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
- Applications
Quantification
- Gene Info — PROC
Entrez GeneID
5624Gene Name
PROC
Gene Alias
PC, PROC1
Gene Description
protein C (inactivator of coagulation factors Va and VIIIa)
Omim ID
176860Gene Ontology
HyperlinkGene Summary
The PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930; MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5; MIM 612309) and VIII (F8; see MIM 306700). Protein S (PROS1; MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM
Other Designations
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- Interactomes
- Pathways
- Diseases
- Publication Reference
- Pathogenic variants of PROC gene caused type I activity deficiency in a familial Chinese venous thrombosis.
Yue Y, Liu S, Han X, Xiao L, Huang Q, Li S, Zhuang K, Yang M, Zou C, Fu Y.
Journal of Cellular and Molecular Medicine 2019 Jul; [Epub].
Application：Quant, Human, ECV‐304, HEK‐293T cells.
- Pathogenic variants of PROC gene caused type I activity deficiency in a familial Chinese venous thrombosis.