TEM8 antibody
Referentie GTX116952-25ul
Formaat : 25ul
Merk : GeneTex
Host | Rabbit |
---|---|
Clonality | Polyclonal |
Isotype | IgG |
Application | WB, IHC-P |
Reactivity | Human |
Package | 100 μl, 25 μl |
View product citations for antibody GTX116952 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
---|---|
WB | 1:500-1:3000 |
IHC-P | 1:100-1:1000 |
Not tested in other applications.
Calculated MW
63 kDa. ( Note )
Positive Control
293T , A431 , HeLa
Predict Reactivity
Mouse, Rat, Bovine(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.72 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the Extracellular domain of human TEM8. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_10721511
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ANTXR cell adhesion molecule 1 , ATR , GAPO , TEM8
Cellular Localization
Cell membrane , Cell projection , lamellipodium membrane , filopodium membrane
Background
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq]
Database
DATA IMAGES
GTX116952 WB Image Sample (30 ug of whole cell lysate) |
GTX116952 IHC-P Image Immunohistochemical analysis of paraffin-embedded human breast cancer, using TEM8(GTX116952) antibody at 1:250 dilution. |