T14284-1mg | β-Amyloid (25-35) [131602-53-4] Clinisciences

β-Amyloid (25-35)

Catalog No. T14284Cas No. 131602-53-4

β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size
1 mg	In Stock
5 mg	In Stock
10 mg	In Stock
25 mg	In Stock
50 mg	In Stock
100 mg	In Stock

Bioactivity

Description	β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.
In vitro	The amino acid sequence of β-Amyloid (25-35) is NH2-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-COOH, where the first Gly represents the amino acid 25 and the last Met represents the amino acid 35 and it is also investigated in gel state for the first time. Amyloid beta-peptide(25-35) induces apoptotic effects on isolated brain mitochondria and the redox state of methionine-35, plays a key role in the induction of programmed cellular death pathways and toxic events[2]. Comparative studies are also carried out using vibrational absorption and ECD. The conformational preference of Aβ(25-35) peptide film is also investigated using vibrational absorption and VCD spectroscopy[1].
In vivo	The Alzheimer' s disease (AD) model group present with spatial learning and memory impairments. CDS and donepezil administration significantly ameliorate the Aβ25–35 peptide-induced memory impairment in both Morris water maze (P?
Alias	β-Amyloid peptide(25-35), Aβ25-35, Amyloid beta-peptide(25-35)

Chemical Properties

Molecular Weight	1060.27
Formula	C45H81N13O14S
Cas No.	131602-53-4

Storage & Solubility Information

Storage

keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 3.33 mg/mL (3.14 mM)

DMSO: 97 mg/mL (91.49 mM)

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	0.9432 mL	4.7158 mL	9.4316 mL	47.1578 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	0.1886 mL	0.9432 mL	1.8863 mL	9.4316 mL
10 mM	0.0943 mL	0.4716 mL	0.9432 mL	4.7158 mL
20 mM	0.0472 mL	0.2358 mL	0.4716 mL	2.3579 mL
50 mM	0.0189 mL	0.0943 mL	0.1886 mL	0.9432 mL
100 mM	0.0094 mL	0.0472 mL	0.0943 mL	0.4716 mL

β-Amyloid (25-35) [131602-53-4]

Référence T14284-1mg

Contactez votre distributeur local :

Marque : TargetMol

Contactez votre distributeur local :

β-Amyloid (25-35)

β-Amyloid (25-35)

Product Introduction

Calculator

In Vivo Formulation Calculator (Clear solution)

Dose Conversion

Tech Support

Keywords

Vous serez peut-être également intéressé par les produits suivants :