General Info
Host: | Rabbit |
Applications: | WB/IHC/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-EPO (93-193) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000IHC-P 1:100-1:200IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | EPO |
Gene ID: | 2056 |
Uniprot ID: | EPO_HUMAN |
Immunogen Region: | 93-193 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 93-193 of human EPO (NP_000790.2). |
Immunogen Sequence: | GLALLSEAVLRGQALLVNSS QPWEPLQLHVDKAVSGLRSL TTLLRALGAQKEAISPPDAA SAAPLRTITADTFRKLFRVY SNFLRGKLKLYTGEACRTGD R |
Description
Tissue Specificity | Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. |
Function | Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. |
Protein Name | ErythropoietinEpoetin |
Database Links | Reactome: R-HSA-1234158Reactome: R-HSA-9006335Reactome: R-HSA-9027276Reactome: R-HSA-9027277Reactome: R-HSA-9027283Reactome: R-HSA-9027284 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Erythropoietin antibodyAnti-Epoetin antibodyAnti-EPO antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance