Anti-LRRC32 (Plato-1) Antibody
Référence OAED00392
Conditionnement : 100ug
Marque : Aviva Systems Biology
Datasheets/Manuals | Printable datasheet for Anti-LRRC32 (Plato-1) Antibody (OAED00392) (OAED00392) Please click here to view the MSDS. |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | LiquidPBS containing 50% glycerol and 0.02% sodium azide |
Clonality | Monoclonal |
Clone | Plato-1 |
Isotype | IgG2b |
Host | Mouse |
Application | Enzyme-linked immunosorbent assay|Immunoprecipitation|Western blot |
Additional Information | 1 test means: 1 uL of MAb is used to stain 500,000 cells in a sample volume of 50 uL. |
Reconstitution and Storage | Store at 4°C short-term. For long-term storage keep unconjugated antibody at -20°C. Avoid freeze/thaw cycles. Protect from light. Stable for at least 1 year after receipt when stored at -20°C. |
Immunogen | Recombinant human LRRC32 (aa 20-627). |
Purification | Protein G-affinity purified |
Concentration | 1 mg/ml |
Specificity | Recognizes human and mouse LRRC32. |
Source | Purified from concentrated hybridoma tissue culture supernatant. |
Application Info | IP: 1:200 WB: 1:1,000 Cited applications include flow cytometry. Optimal dilutions should be determined by the end user. |
Reference | Blocking immunosuppression by human Tregs in vivo with antibodies targeting integrin αVβ8: J. Stockis, et al.; PNAS 114, E10161 (2017) A key role of GARP in the immune suppressive tumor microenvironment: S.A. Hahn, et al.; Oncotarget 7, 42996 (2016), Application(s): Western blot Surface Expression of TGFβ Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer: A. Metelli, et al.; Cancer Res. 76, 7106 (2016) Lysosomal-associated Transmembrane Protein 4B (LAPTM4B) Decreases Transforming Growth Factor β1 (TGF-β1) Production in Human Regulatory T Cells: C. Huygens, et al.; J. Biol. Chem. 290, 20105 (2015) |
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Gene Symbol | LRRC32 |
Gene Full Name | leucine rich repeat containing 32 |
Alias Symbols | CPPRDD;D11S833E;GARP;garpin;glycoprotein A repetitions predominant;leucine-rich repeat-containing protein 32;transforming growth factor beta activator LRRC32. |
NCBI Gene Id | 2615 |
Protein Name | Leucine-rich repeat-containing protein 32 |
Description of Target | LRRC32 (leucine rich repeat containing 32; also known as GARP or Garpin; Glycoprotein A repetitions predominant) is a glycoprotein expressed on the cell surface of megakaryocytes, platelets and activated regulatory T (Treg) cells. |
Uniprot ID | Q14392 |
Molecular Weight | Detects a band of ~100kDa (Fc Fusion OPED00084) by Western blot. Native protein is ~72kDa. |
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What is the species homology for "Anti-LRRC32 (Plato-1) Antibody (OAED00392)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "Anti-LRRC32 (Plato-1) Antibody (OAED00392)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 week".
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What buffer format is "Anti-LRRC32 (Plato-1) Antibody (OAED00392)" provided in?
This item is provided in "LiquidPBS containing 50% glycerol and 0.02% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Anti-LRRC32 (Plato-1) Antibody (OAED00392)"?
This target may also be called "CPPRDD;D11S833E;GARP;garpin;glycoprotein A repetitions predominant;leucine-rich repeat-containing protein 32;transforming growth factor beta activator LRRC32." in publications.
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What is the shipping cost for "Anti-LRRC32 (Plato-1) Antibody (OAED00392)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
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What is the guarantee for "Anti-LRRC32 (Plato-1) Antibody (OAED00392)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Anti-LRRC32 (Plato-1) Antibody (OAED00392)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Detects a band of ~100kDa (Fc Fusion OPED00084) by Western blot. Native protein is ~72kDa.".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Anti-LRRC32 (Plato-1) Antibody (OAED00392)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "LRRC32"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "LRRC32"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "LRRC32"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "LRRC32"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "LRRC32"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "LRRC32"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.