Anti-SYP antibody (250-350) {Biotin}

Clonality:	Polyclonal
Conjugation:	Biotin
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.60-0.62 µg/µl
Dilution Range:	WB: 1:1, 000 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:125 IHC: 1:100 ICC: 1:100 IF: 1:100 CFM: 1:100
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	SYP
Gene ID:	6855
Uniprot ID:	SYPH_HUMAN
Immunogen Region:	250-350
Immunogen:	Synthetic peptide taken within amino acid region 250-350 on human Synaptophysin protein.

Tissue Specificity	Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3. Expressed in the putamen (at protein level).
Post Translational Modifications	Ubiquitinated.mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. Phosphorylated by SRC.
Function	Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Protein Name	Synaptophysin Major Synaptic Vesicle Protein P38
Database Links	Reactome: R-HSA-9662360
Cellular Localisation	Cytoplasmic Vesicle Secretory Vesicle Synaptic Vesicle Membrane Multi-Pass Membrane Protein Synapse Synaptosome
Alternative Antibody Names	Anti-Synaptophysin antibody Anti-Major Synaptic Vesicle Protein P38 antibody Anti-SYP antibody

Information sourced from Uniprot.org

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