beta Tubulin 3/ Tuj1 antibody [TU-20] (FITC)
Référence GTX78442-100ug
Conditionnement : 100ug
Marque : Genetex
Host | Mouse |
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Clonality | Monoclonal |
Clone Name | TU-20 |
Isotype | IgG1 |
Application | ICC/IF, FACS, IHC |
Reactivity | Human, Mouse, Rat, Bovine, Hamster, Pig, Baboon, Carp |
Package | 100 μg |
View product citations for antibody GTX78442 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
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ICC/IF | Assay dependent |
FACS | Assay dependent |
IHC | Assay dependent |
Not tested in other applications.
Calculated MW
50 kDa. ( Note )
Product Note
This antibody recognizes C-terminal peptide sequence ESESQGPK (aa 441-448) of neuron-specific human betaIII-tubulin.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide (C) 441-448 coupled to maleimide-activated keyhole limpet hemocyanin via cysteine added to the N-terminus of the neuron-specific peptide.
Purification
Purified by size-exclusion chromatography
Conjugation
Fluorescein isothiocyanate (FITC)
RRID
AB_625754
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CDCBM , CDCBM1 , CFEOM3 , CFEOM3A , FEOM3 , TUBB3 , TUBB4 , beta4 , tubulin beta 3 class III , Beta III tubulin , Tuj1 , beta tubulin 3 , Tuj-1
Cellular Localization
Cytoplasm,Cytoskeleton
Background
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]
Database
DATA IMAGES
GTX78442 ICC/IF Image ICC/IF analysis of Neuro2a cells using GTX78442 beta Tubulin 3/ Tuj1 antibody [TU-20] (FITC). |
Application Reference
Park JH et al. J Korean Neurosurg Soc 2012; 52 (3) : 246-9 Intracranial extraskeletal myxoid chondrosarcoma : case report and literature review.
Application : IHC
Clone Reference
Schaefers C et al. Stem Cells Int 2022; 2022:1320950 The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons.
Liu KC et al. Oncotarget 2013; 4 (12):2366-82 Ovarian cancer stem-like cells show induced translineage-differentiation capacity and are suppressed by alkaline phosphatase inhibitor.
Lehmann M et al. PLoS One 2013; 8 (8):e70913 Evidence for a critical role of catecholamines for cardiomyocyte lineage commitment in murine embryonic stem cells.
Chien HC et al. PLoS One 2012; 7 (10):e47481 Targeted disruption in mice of a neural stem cell-maintaining, KRAB-Zn finger-encoding gene that has rapidly evolved in the human lineage.
Submit a Reference REVIEW
Application Reference
Park JH et al. J Korean Neurosurg Soc 2012; 52 (3):246-9 Intracranial extraskeletal myxoid chondrosarcoma : case report and literature review.
Application : IHC
Jung G et al. The Korean Journal of Pathology. 2011; 45:S101-105 Dedifferentiated Extraskeletal Myxoid Chondrosarcoma of the Masticator Space - A Case Report.
Application : IHC
Reactivity : Human
Clone Reference
Schaefers C et al. Stem Cells Int 2022; 2022:1320950 The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons.
Liu KC et al. Oncotarget 2013; 4 (12):2366-82 Ovarian cancer stem-like cells show induced translineage-differentiation capacity and are suppressed by alkaline phosphatase inhibitor.
Lehmann M et al. PLoS One 2013; 8 (8):e70913 Evidence for a critical role of catecholamines for cardiomyocyte lineage commitment in murine embryonic stem cells.
Chien HC et al. PLoS One 2012; 7 (10):e47481 Targeted disruption in mice of a neural stem cell-maintaining, KRAB-Zn finger-encoding gene that has rapidly evolved in the human lineage.
SDS | |
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PBS.pdf | |
Sodium Azide.pdf |