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FITC Anti-Human CD86 Monoclonal Antibody (Clone : BU63)

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Référence FITC-30042-50T

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G6PD clia kit :: Human G6PD (Glucose 6 Phosphate Dehydrogenase) CLIA Kit

Typical Testing Data/Standard Curve (for reference only)
Product Name

G6PD (Glucose 6 Phosphate Dehydrogenase), CLIA Kit

Full Product Name

Human G6PD (Glucose 6 Phosphate Dehydrogenase) CLIA Kit

Product Gene Name

G6PD clia kit

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sample Manual Insert
Download Sample PDF Manual View Sample PDF Manual
Request for Current Manual Insert
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MBS2532759 COA
COA PDF
MBS2532759 Testing Data
Testing Data PDF
MBS2532759 QC Report
QC Report PDF
MBS2532759 MSDS
MSDS PDF
MBS2532759 Technical Datasheet
Technical Datasheet PDF
MBS2532759 Protocol
Protocol PDF
Molecular Weight
62,468 Da
OMIM
300908
Species Reactivity
Human
Specificity
This kit recognizes natural and recombinant G6PD. No significant cross-reactivity or interference between G6PD and analogues was observed.
Assay Type
Sandwich
Detection Range
62.5-4000pg/mL
Sensitivity
Min: 37.5pg/mL; Max: 4000pg/mL
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Other Notes
Small volumes of G6PD clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
G6PD clia kit
Intended Uses: This CLIA kit applies to the in vitro quantitative determination of G6PD concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to G6PD. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for G6PD and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain G6PD, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of G6PD. You can calculate the concentration of G6PD in the samples by comparing the RLU value of the samples to the standard curve.
Typical Testing Data/Standard Curve (for reference only) of G6PD clia kit
G6PD clia kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS2532759.
NCBI/Uniprot data below describe general gene information for G6PD. It may not necessarily be applicable to this product.
NCBI GI #
182890
NCBI GeneID
2539
NCBI Accession #
AAA63175.1
NCBI Official Synonym Symbols
G6PD1
  
NCBI Protein Information
glucose-6-phosphate 1-dehydrogenase
UniProt Protein Name
Glucose-6-phosphate 1-dehydrogenase
UniProt Gene Name
G6PD  
UniProt Synonym Gene Names
G6PD  
UniProt Entry Name
G6PD_HUMAN
NCBI Summary for G6PD
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for G6PD
G6PD: glucose-6-phosphate dehydrogenase. A cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two splice variant isoforms have been described. The long isoform is found in lymphoblasts, granulocytes and sperm.

Protein type: Carbohydrate Metabolism - pentose phosphate pathway; Oxidoreductase; EC 1.1.1.49; Cell development/differentiation; Other Amino Acids Metabolism - glutathione

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: centrosome; internal side of plasma membrane; membrane; intracellular membrane-bound organelle; cytoplasm; microtubule organizing center; nucleus; cytosol

Molecular Function: identical protein binding; glucose-6-phosphate dehydrogenase activity; protein binding; protein homodimerization activity; NADP binding; glucose binding

Biological Process: NADPH regeneration; response to food; pentose-phosphate shunt; transcription initiation from RNA polymerase II promoter; erythrocyte maturation; ribose phosphate biosynthetic process; pentose-phosphate shunt, oxidative branch; glucose 6-phosphate metabolic process; glucose metabolic process; NADP metabolic process; cholesterol biosynthetic process; response to organic cyclic substance; substantia nigra development; glutathione metabolic process; response to ethanol; carbohydrate metabolic process; regulation of neuron apoptosis; gene expression; lipid metabolic process; pentose biosynthetic process

Disease: Favism, Susceptibility To; Anemia, Nonspherocytic Hemolytic, Due To G6pd Deficiency; Malaria, Susceptibility To
Research Articles on G6PD
1. 53 G6PD polymorphisms, including 202/376, were genotyped across the 712 samples from Dogon and Fulani people. Association of these polymorphisms and mild malaria was assessed in both ethnic groups using genotypic and haplotypic statistical tests.