Human Herpes Virus 8 (HHV8)(LN53), Biotin conjugate, 0.1mg/mL

Référence BNCB1746-100

Conditionnement : 100uL

Marque : Biotium

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Antibody number

#1746

Antibody reactivity (target)

Human Herpes Virus 8

Antibody type

Primary

Host species

Rat

Clonality

Monoclonal

Clone

LN53

Isotype

IgG2c, kappa

Molecular weight

Not Known

Synonyms

HHV8; Human Herpes Virus 8; Human herpesvirus 8; Kaposi’s sarcoma associated herpes virus; KSHV

Human gene symbol

Not Applicable

Entrez gene ID

Not Applicable

SwissProt

Not Applicable

Unigene

Not Applicable

Immunogen

Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8

Species reactivity

HHV8

Antibody application notes

For coating for ELISA, order Ab without BSA, Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody, Optimal dilution and staining procedure for a specific application should be determined by user, Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

Positive control

Herpes simplex type 1 (HSV-1) extract or infected cells. Tissue.

Shipping condition

Room temperature

Storage Conditions

Note: store BSA-free antibodies at -10 to -35°C, Store at 2 to 8 °C, Protect fluorescent conjugates from light

Regulatory status

For research use only (RUO)

Antibody/conjugate formulation

Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA, Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide

Shelf life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Product origin

Product may contain either bovine serum albumin (BSA) from bovine serum (Bos taurus), or recombinant BSA produced in Chinese hamster ovary cells. Inquire for the specific lot.

Tumor expression

Leukemia/lymphoma, Sarcoma

Download Datasheet

Product Description

HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi’s sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman’s disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.

Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the

CF® Dye Brochure

for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Stock status: Because Biotium offers a large number of antibody and conjugation options, primary antibody conjugates may be made to order. Typical lead times are up to one week for CF® dye and biotin conjugates, and up to 2-3 weeks for fluorescent protein and enzyme conjugates. Please email

info@clinisciences.com

to inquire about stock status and lead times before placing your order.

 Catalog number key for antibody number 1746, Anti-Human Herpes Virus 8 (LN53) 

Antibody # prefix Conjugation Ex/Em (nm) Laser line Detection channel Dye Features
BNC04 CF®405S 404/431 405 DAPI (microscopy), AF405

CF®405S Features

BNC88 CF®488A 490/515 488 GFP, FITC

CF®488A Features

BNC68 CF®568 562/583 532, 561 RFP, TRITC

CF®568 Features

BNC94 CF®594 593/614 561 Texas Red®

CF®594 Features

BNC40 CF®640R 642/662 633-640 Cy®5

CF®640R Features

BNC47 CF®647 650/665 633-640 Cy®5

CF®647 Features

BNC74 CF®740 742/767 633-685 775/50

CF®740 Features

BNCB Biotin N/A N/A N/A
BNUB Purified N/A N/A N/A
BNUM Purified,
BSA-free
N/A N/A N/A
Alexa Fluor, Pacific Blue, Pacific Orange, and Texas Red are trademarks or registered trademarks of Thermo Fisher Scientific; Cy is a registered trademark of Cytiva; IRDye, LI-COR, and Odyssey are registered trademarks of LI-COR Bioscience.