600145 | Human IL-33 Clinisciences

Recombinant Active Protein

Cat. No.

600145

Unit

0.01 mg

Description

Interleukin-33 (IL-33) binds to IL1RL1/ST2 and activates a signaling pathway involving MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAP kinases. IL-33 induces T helper type-2 associated cytokines. Recombinant Human IL-33 produced in E. coli is a non-disulfide-linked homodimeric non-glycosylated polypeptide chain consisting of 160 amino acids with a MW of 18,125 Da.

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Datasheet

Format

Each vial contains 10 ug protein lyophilized in 10 mM sodium phosphate pH7.5. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Alternate Names

Interleukin-33; IL-33; interleukin-1 family member 11; IL-1F11; Nuclear factor from high endothelial venules; NF-HEV; IL33; C9orf26; NFHEV

Accession No.

O95760

18125 Da

Sequence

MSITGISPIT EYLASLSTYN DQSITFALED ESYEIYVEDL KKDEKKDKVL LSYYESQHPS NESGDGVDGK MLMVTLSPTK DFWLHANNKE HSVELHKCEK PLPDQAFFVL HNMHSNCVSF ECKTDPGVFI GVKDNHLALI KVDSSENLCT ENILFKLSET

Source

E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.

Purity

Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm. Quantitation on SDS-PAGE against a known standard.

Storage

Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.

Images

For research use only, not for diagnostic or therapeutic procedures.

Human IL-33

Référence 600145

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Marque : Abbiotec

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