Human sphingosine 1 phosphate phosphatase 1 (SGPP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SGPP1
Locus ID	81537
Kit Components	GA113051G1, sphingosine 1 phosphate phosphatase 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113051G2, sphingosine 1 phosphate phosphatase 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113051G3, sphingosine 1 phosphate phosphatase 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_030791
UniProt ID	Q9BX95
Synonyms	SPPase1
Summary	Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied by OMIM, Jun 2009]