Réactifs et instruments pour l'immunologie, la biologie cellulaire et la biologie moléculaire.

O-Desethyl Dapagliflozin [864070-37-1]

Imprimer

Référence T67849-50mg

Conditionnement : 50mg

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Marque : TargetMol

Contactez votre distributeur local :

Téléphone : +1 850 650 7790

O-Desethyl Dapagliflozin

Purity:97.09%

Resource Download

COA HPLC HNMR

O-Desethyl Dapagliflozin

Catalog No. T67849Cas No. 864070-37-1

O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size
1 mg
5 mg
10 mg
25 mg
50 mg
100 mg
1 mL x 10 mM (in DMSO)

Product Introduction

Bioactivity

Description	O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.
Targets&IC50	SGLT2:33 nM
Alias	Empagliflozin-4

Chemical Properties

Molecular Weight	380.82
Formula	C19H21ClO6
Cas No.	864070-37-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 27.5 mg/mL (72.21 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6259 mL	13.1296 mL	26.2591 mL	131.2956 mL
5 mM	0.5252 mL	2.6259 mL	5.2518 mL	26.2591 mL
10 mM	0.2626 mL	1.3130 mL	2.6259 mL	13.1296 mL
20 mM	0.1313 mL	0.6565 mL	1.3130 mL	6.5648 mL
50 mM	0.0525 mL	0.2626 mL	0.5252 mL	2.6259 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

O-Desethyl Dapagliflozin